The Polycomb landscape in mouse development
نویسندگان
چکیده
Polycomb-group proteins assemble into two primary complexes—Polycomb repressive complex (PRC) 1 and 2—that safeguard cell fate by repressing gene transcription. Two new studies explore the PRC1 landscape during transition from gametes to embryos in mice, thus providing insight intergenerational transmission of epigenetic information regulation dynamics as prepare for gastrulation.
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ژورنال
عنوان ژورنال: Nature Genetics
سال: 2021
ISSN: ['1546-1718', '1061-4036']
DOI: https://doi.org/10.1038/s41588-021-00833-y